Forty Patients Men (aged 16-23 years old) must be in good general health with mild-to-moderate facial acne were included in this study. Men, with mild-to-moderate facial acne, aged 16-23 years old
Conditions
Interventions
Applied the herbal gel to the affected area of the face once daily before bed for four weeks. ,Applied the clindalin gel to the affected area of the face once daily before bed for four weeks.
Experimental Drug,Active Comparator Drug
herbal gel (active ingredinet compost of ethanol extract of Curcuma longa, Acanthus ebracteatus, Quercus infectoria ) ,clindalin gel
Sponsors
Private research funding
Eligibility
Sex/Gender
Male
Age
16 Years to 23 Years
Inclusion criteria
Inclusion criteria: 1. 40 Patients Men (aged 16-23 years old) must be in good general health with mild-to-moderate facial acne were included in this study. 2.40 patients were random into two groups the group one 20 patients were treated with herbal gel and in group two 20 patients were treated with Clindamycin. 3. Before the study, all participants underwent an allergy test on the forearm to assess potential hypersensitivity. Allergy Testing Procedure 1. A patch test was performed on the inner forearm of each participant prior to treatment initiation. 2. A small amount of the herbal gel was applied to a square centimeter area of the skin and covered with an occlusive dressing for 24 hours 3. The site was then evaluated for signs of allergic reaction, including erythema, swelling, itching, or rash. 4. Participants who exhibited any of these symptoms were excluded from the study.
Exclusion criteria
Exclusion criteria: 1. The patient has a history of sensitivity to any of the ingredients in the test articles such as Acanthus ebracteatus (leaves and stem), Curcuma longa (rhizome), and Quercus infectoria (gall). 2. Use topical anti-acne medication or procedures on the face over the past two weeks. 3. Use of topical anti-acne preparations or procedures on the face during study. 4. Use of systemic antibiotics for acne treatment in the study 5. found a cyst, nodule, or sinus tract 6. skin pathology or condition that, in the investigator's opinion, could interfere with the evaluation of the test article or requires the use of interfering topical, systemic, or surgical therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| acne severity 4 week The Investigator Global Assessment (IGA) scale is a measure of acne severity | — |
Secondary
| Measure | Time frame |
|---|---|
| acne lesions 4 week count | — |
Countries
Thailand
Contacts
Public ContactKingan Luepuech
School of medicine
Outcome results
None listed