Skip to content

Intraoperative wound irrigation with aqueous povidone-iodine for reduction of incisional surgical site infection in emergency laparotomy

Intraoperative wound irrigation with aqueous povidone-iodine for reduction of incisional surgical site infection in emergency laparotomy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250412001
Enrollment
368
Registered
2025-04-12
Start date
2025-04-05
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Incisional surgical site infection after emergency laparotomy Re-operation 30-day mortality Surgical site infection Povidone Iodine Laparotomy

Interventions

Intraoperative wound irrigation with 10% aqueous povidone iodine is performed for one minute before skin closure,Intraoperative wound irrigation with 0.9% NaCl is performed as usual before skin closur
10% povidone iodine,0.9% Nacl

Sponsors

Pongsakorn Srichan, Surin Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Adult patients age morethan 18 year who are undergoing emergency laparotomy in Surin hospital. 2. Patients can provide inform consent and have to be able to attended follow up.

Exclusion criteria

Exclusion criteria: 1. Identified of bacterial infection in the surgical field prior surgery 2. Laparoscopic surgery 3. Revision surgery (previous abdominal surgery within 30 days or plan to repeat surgery within 30 days after inclusion) 4. Temporary open abdomen 5. Preoperative continuous antibiotic within 5 days before surgery 6. Allergy to povidone-iodine 7. Pregnancy

Design outcomes

Primary

MeasureTime frame
Incisional surgical site infection 30 day after operation Clinical sign, pus culture

Secondary

MeasureTime frame
mortality 30 day after operation Number of dead

Countries

Thailand

Contacts

Public ContactPongsakorn Srichan

Surin Hospital

ash.pongsa@gmail.com0918791595

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026