Children undergoing Elective Daycare Surgery Paediatric surgery, TIVA, Propofol and ketamine.
Conditions
Interventions
patients will receive ketamine bolus @ 0.5 mg/kg and infusion @ 0.25 mg/kg/hr and propofol-TCI set at plasma target value of 3-5 mcg/ml to maintain BIS between 40-60. ,patient will receive normal sa
Active Comparator Drug,Active Comparator Drug
Propofol-ketamine (PK),Propofol (P)
Sponsors
Department of Anaesthesia, Sir Gangaram Hospital, New Delhi
Eligibility
Sex/Gender
All
Age
1 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Age: 1-12 years 2. ASA physical status I and II. 3. Patients undergoing infra umbilical day care surgery.
Exclusion criteria
Exclusion criteria: 1. Parents or guardians refusal 2. ASA III and more 3. Known allergy or hypersensitivity to the drugs in study 4. Difficult IV access or refusal to IV cannulation while being awake. 5. Any developmental delay or neuropsychiatric illness 6. Congenital heart disease or coagulation disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Propofol requirement with TCI-propofol with or without ketamine End of surgery Assessed by monitoring total propofol consumption | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative hemodynamic parameters At every 5 minutes till end of surgery Heart rate, mean blood pressure every minutes ,Post op sedation 30 mins, 1 and 2 hours postoperatively Ramsay sedation scale,Side effects Score at 1 hour, and 2 hours postoperatively Assessment of any secretions, post operative nausea and vomiting, emergence delirium using PAEDS scale,Discharge criteria At 2 hours post operatively. Modified Aldrete score | — |
Countries
India
Contacts
Public ContactDeepanjali Pant
Sir Gangaram hospital
Outcome results
None listed