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Effect of Antibiotic Prophylaxis After Flexible Cystoscopy to Prevent Symptomatic Urinary Tract Infection: A Randomized Controlled Trial

Effect of Antibiotic Prophylaxis After Flexible Cystoscopy to Prevent Symptomatic Urinary Tract Infection: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250402004
Enrollment
284
Registered
2025-04-02
Start date
2024-08-26
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

To evaluate the efficacy of no antibiotic prophylaxis compared to antibiotic prophylaxis in preventing symptomatic urinary tract infections (UTIs) following flexible cystoscopy Urinary tract infection Antibiotic prophylaxis

Interventions

cefixime 100 mg adjusted by renal clearance,no antibiotic
Active Comparator Drug,No Intervention No treatment
Antibiotic prophylaxis,no Antibiotic prophylaxis

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1 aged over 18 years 2 met the indication for flexible cystoscopy

Exclusion criteria

Exclusion criteria: 1 pregnancy 2 patients with a urinary catheter 3 cephalosporin antibiotic allergy 4 ongoing symptoms of a urinary tract infection 5 the need for additional procedures during flexible cystoscopy 6 active infection, active smoking 7 active cardiovascular disease 8 active cerebrovascular disease 9 immunocompromised patients, such as those undergoing chemotherapy or using steroids 10 COPD 11 bedridden status 12 abnormal urinary tract anatomy 13 creatinine clearance (CrCl) less than 20 mL/min.

Design outcomes

Primary

MeasureTime frame
Urinary tract infection symptom 7days phone call ask about urinary tract infection symptom

Secondary

MeasureTime frame
Urinary tract infection symptom 7days symptom phone call ask about urinary tract infection symptom

Countries

Thailand

Contacts

Public ContactAtiya Seeluangsawat

Faculty of Medicine, Chulalongkorn University

atiya.see@chulahospital.org022564568

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026