Skip to content

Comparison of Lidocaine Spray alone or in combination with Anti-inflammatory Throat spray (Difflam Forte) in Patients Undergoing Unsedated Esophagogastroduodenoscopy: A Randomized Controlled Trial

Comparison of Lidocaine Spray alone or in combination with Antiinflammatory Throat spray in Patients Undergoing Unsedated Esophagogastroduodenoscopy: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250329002
Enrollment
44
Registered
2025-03-29
Start date
2024-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Unsedated Esophagogastroduodenoscopy Unsedated Esophagogastroduodenoscopy, Lidocaine Spray, Anti-inflammatory Throat spray

Interventions

A placebo spray of normal saline, followed by two puffs of lidocaine spray on the left, right, and center of the oropharynx using a tongue depressor,An anti-inflammatory throat spray, followed by two
Placebo Comparator Drug,Active Comparator Drug
Lidocaine Spray ,Lidocaine Spray combination with Anti-inflammatory Throat spray

Sponsors

Arunluk Buranathawornsom
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1.Patients aged 15 years and older. 2.Patients undergoing upper gastrointestinal endoscopy at Yala Regional Hospital. 3.Indications for diagnostic endoscopy include cancer screening and evaluation of symptoms such as dysphagia, indigestion, gastroesophageal reflux, abdominal pain, or anemia. 4.Patients undergoing endoscopy must not receive intravenous sedation. 5.Patients must consent to participate in the research study

Exclusion criteria

Exclusion criteria: (1) Head and neck cancer patients (2) Previous surgery of the upper aerodigestive tract (3) corrosive ingestion (4) Pregnant (5) Contraindications for EGD (6) Allergy to medications, lidocaine, or NSAID (7) Psychiatric problem, neuromuscular disorder (8) Emergency conditions or with unstable vital signs.

Design outcomes

Primary

MeasureTime frame
the patient satisfaction, pain, and discomfort 6 to 12 months STATA MP 18

Secondary

MeasureTime frame
endoscopist's satisfaction, the endoscopist's perception of the patient's tolerance, ease of endoscope insertion, procedure duration, successful endoscopy, and adverse events. 6 to 12 months STATA MP 18

Countries

Thailand

Contacts

Public ContactArunluk Buranathawornsom

Yala hospital

Arunluk2530@gmail.com0894746825

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026