Comparison duration of endotracheal tube cuff pressure change to critical value during laparoscopic abdominal surgeries among patients receiving nitrous oxide in different ratio

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20250323005

Enrollment

Registered

2025-03-23

Start date

2021-09-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients receiving nitrous oxide in different ratio during laparoscopic abdominal surgeries Laparoscopic abdominal surgeries, Endotracheal tube cuff pressure

Interventions

nitrous oxide 60% , nitrous oxide 50%

Experimental Drug,Experimental Drug

nitrous oxide in different ratio, nitrous oxide in different ratio

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-65 years old, 2. ASA physical status 1-3, 3.BMI 18.5-30 kg/m2, 4. Elective laparoscopic surgery

Exclusion criteria

Exclusion criteria: 1.Respiratory tract infection within 2 wks. of surgery, 2. Risk of aspiration, 3. Contraindication for nitrous oxide, sevoflurane, 4. Suspected difficult intubation, 5. Pulmonary disease or airway problem

Design outcomes

Primary

Measure	Time frame
Time to endotracheal tube cuff pressure change to critical value After closed nitrous oxide Pilot balloon was connected to the manometer to measure cuff pressure	—

Secondary

Measure	Time frame
The amount of air remove from the endotracheal tube cuff. After closed nitrous oxide Volume of air removed from cuff pressure	—

Countries

Thailand

Contacts

Public ContactBenjawan Naklamai

Faculty of Medicine, Srinakharinwirot University

naklamaibenjawan@gmail.com66918841818

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026