Effects of Low-Dose Caffeine on Brainwave Activity and Cognitive Responses Following Fatigue in Taekwondo Athletes: A Randomized Controlled Study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

TCTR

Registry ID

TCTR20250319009

Enrollment

Registered

2025-03-19

Start date

2019-12-02

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy male university Taekwondo athletes Cognitive performance, Physical Fatigue, Brain Activity, Auditory P300 Event-Related Potentials, Skill-based sports

Interventions

200 mg of caffeine (two 100 mg capsules),an identical placebo

Experimental Dietary Supplement,Placebo Comparator Dietary Supplement

the caffeine (CAF) ,the placebo (PLA)

Eligibility

Sex/Gender

Male

Age

18 Years to 25 Years

Inclusion criteria

Inclusion criteria: 1. participants to have a maximal oxygen uptake (VO2max) greater than 40 ml/kg/min, 2. between 2 and 5 years of Taekwondo training experience, 3. a training volume of 9 to 15 hours per week, 4. collegiate competition experience, and 5. low habitual caffeine intake (<150 mg/day).

Exclusion criteria

Exclusion criteria: 1. had a history of clinical diseases, 2. had musculoskeletal disorders, 3. had adverse reactions to caffeine, or 4. had medication use in the three months preceding the study.

Design outcomes

Primary

Measure	Time frame
Heart rate (HR) baseline (pre-Sup), post-supplementation (post-Sup), and at each round (r1, r2, r3) of the Taekwondo exercise protocol a chest strap telemetry device ,Rating of perceived exertion (RPE) baseline (pre-Sup), post-supplementation (post-Sup), and at each round (r1, r2, r3) of the Taekwondo exercise protocol Borg scale,Blood glucose (BG) baseline (pre-Sup), post-supplementation (post-Sup), and at each round (r1, r2, r3) of the Taekwondo exercise protocol using an ACCU-CHEK glucose meter (Switzerland) ,Blood lactate (BL) levels baseline (pre-Sup), post-supplementation (post-Sup), and at each round (r1, r2, r3) of the Taekwondo exercise protocol a Lactate Scout analyzer (Germany),Electroencephalogram (EEG) baseline (pre-Sup), post-supplementation (post-Sup), and post-fatigue induction (post-I) the eegosports system,Auditory P300 Event-Related Potentials (ERPs) baseline (pre-Sup), post-supplementation (post-Sup), and post-fatigue induction (post-I) the eegosports system	—

Measure

Time frame

Heart rate (HR) baseline (pre-Sup), post-supplementation (post-Sup), and at each round (r1, r2, r3) of the Taekwondo exercise protocol a chest strap telemetry device ,Rating of perceived exertion (RPE) baseline (pre-Sup), post-supplementation (post-Sup), and at each round (r1, r2, r3) of the Taekwondo exercise protocol Borg scale,Blood glucose (BG) baseline (pre-Sup), post-supplementation (post-Sup), and at each round (r1, r2, r3) of the Taekwondo exercise protocol using an ACCU-CHEK glucose meter (Switzerland) ,Blood lactate (BL) levels baseline (pre-Sup), post-supplementation (post-Sup), and at each round (r1, r2, r3) of the Taekwondo exercise protocol a Lactate Scout analyzer (Germany),Electroencephalogram (EEG) baseline (pre-Sup), post-supplementation (post-Sup), and post-fatigue induction (post-I) the eegosports system,Auditory P300 Event-Related Potentials (ERPs) baseline (pre-Sup), post-supplementation (post-Sup), and post-fatigue induction (post-I) the eegosports system

—

Secondary

Measure	Time frame
Taekwondo-Specific Agility Test (TSAT) baseline (pre-Sup), post-supplementation (post-Sup), and post-fatigue induction (post-I) reaction time (RT), percent accuracy, and agility	—

Countries

Thailand

Contacts

Public ContactAmornpan Ajjimaporn

Mahidol University

g4036011@gmail.com0838555647

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026