Healthy conditions Healthy adults
Conditions
Interventions
Turmeric/EGCG emulgel at two concentrations, blank emulgel (vehicle), and 0.9% saline solution (negative control)
Experimental Drug
Turmeric/EGCG emulgel
Sponsors
Chiang Mai University
Thailand Science Research and Innovation
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Healthy male or female, aged 20-60 years 2. Able to understand and provide written informed consent
Exclusion criteria
Exclusion criteria: 1. Pregnant or nursing 2. History of dermatological conditions 3. Fitzpatrick phototypes V or VI 4. Using systemic or topical treatments 5. Using vitamin A acid or its derivative 6. Skin marks at the proposed test area 7. Significant diseases or medical conditions 8. Immunocompromised 9. Unwilling or unable to comply with the lifestyle consideration 10. Bathe, sauna, water sports, or activities causing intense sweating 11. Vaccination 12. Participating in other studies 13. Intolerance or hypersensitivity to any ingredient in the study products
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin irritation Days 3, 5, 8, 10, 12, 15, 17, 19, 22 Draize dermal irritation scoring system,Skin sensitization Days 38, 40 International Contact Dermatitis Research Group (ICDRG) scoring system | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse effects Days 1, 3, 5, 8, 10, 12, 15, 17, 19, 22, 36, 38, 40 History taking and physical examination | — |
Countries
Thailand
Contacts
Public ContactNut Koonrungsesomboon
Chiang Mai University
Outcome results
None listed