Premature luteinizing hormone surge in infertile women with normal ovarian reserve undergoing controlled ovarian stimulation in fixed and flexible PPOS protocols Fixed PPOS, flexible PPOS, premature LH surge
Conditions
Interventions
In the flexible PPOS protocol, medroxyprogesterone acetate 10 mg is started at a dosage of one tablet once a day when dominant follicles reach 14 millimeters or serum estradiol levels are equal or mor
Experimental Drug,Active Comparator Drug
Flexible PPOS,Fixed PPOS
Sponsors
Fund of Faculty of Medicines
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. An infertile women with normal ovarian reserve according to Poseidon criteria Group 1 defined by age less than 35 years old and AMH equal or more than 1.2 ng/dL or an antral follicle count equal or more than 5, undergoing IVF/ICSI 2. An infertile women with normal ovarian reserve according to Poseidon criteria Group 2 defined by age equal or more than 35 years old and AMH equal or more than 1.2 ng/dL or an antral follicle count equal or more than 5, undergoing IVF/ICSI
Exclusion criteria
Exclusion criteria: 1. Women with a history of progestin drug allergy or contraindications to progestin hormone therapy 2. Women with a canceled ovarian stimulation cycle, such as in whom no eggs were retrieved
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Premature luteinizing hormone surge Before ovulation trigger Serum luteinizing hormone | — |
Secondary
| Measure | Time frame |
|---|---|
| Total number of oocytes After ovarian pick-up Count oocytes after ovarian pick-up,Number of metaphase II oocytes After intracytoplasmic sperm injection Count metaphase II oocytes after intracytoplasmic sperm injection,Fertilization rate After intracytoplasmic sperm injection Count fertilized eggs after fertilization,Number of 2 pronuclear embryos After intracytoplasmic sperm injection day 1 count 2 pronuclear embryos after intracytoplasmic sperm injection 1 day,Number of cleavage stage embryos After intracytoplasmic sperm injection day 3 Count embryos in cleavage stage in day 3 after intracytoplasmic sperm injection,Number of blastocyst embryos After intracytoplasmic sperm injection day 5 Count blastocyst embryos after intracytoplasmic sperm injection day 5 | — |
Countries
Thailand
Contacts
Public ContactRatsak Tangterdchanakit
Khon Kaen University
Outcome results
None listed