Restless legs syndrome in hemodialysis patients Restless legs syndrome, hemodialysis, end stage kidney disease, intradialytic exercise, gabapentin
Conditions
Interventions
Intradialytic quadriceps strengthening exercises in each hemodialysis sessions for 12 weeks combined with gabapentin 100 mg per day ,gabapentin 100 mg per day
Intradialytic strengthening exercises combined with gabapentin ,Gabapentin alone
Sponsors
Phramongkutklao hospital, Thailand
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 20 years old or older, 2. End stage renal disease patients undergoing hemodialysis at least 3 months with adequate dialysis delivery, 3. Diagnosis of Restless legs syndrome based on international RLS study Group, 4. Persistent Restless legs syndrome symptoms occurring at least twice per week , 5. Informed consent
Exclusion criteria
Exclusion criteria: 1. Use of gabapentin or dopamine agonists for restless legs syndrome treatment within the past 12 weeks 2.Ferritin level < 200 ng/ml, 3.Pregnancy , 4.Diagnostic of depression or psychiatric disorder, 5.Obstructive sleep apnea , 6.Physical limitations such as leg amputation, 7.Unstable patients or critical illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in international Restless legs syndrome study group severity scale and grading between groups 12 weeks international Restless legs syndrome study group rating scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life and sleep quality 12 weeks Kidney disease specific quality of life 36 questionnaires (KDQOL-36), Epworth sleepiness score questionnaires | — |
Countries
Thailand
Contacts
Public ContactSiriwan Sornseney
Phramongkutklao Hospital
Outcome results
None listed