The orthodontic patients ( more than 18 years old) who will be received fixed orthodontic appliance or Invisalign treatment. Fixed orthodontic appliance, Invisalign, salivary proteomics, biomarkers, LC/MS-MS
Conditions
Interventions
Patients received fixed orthodontic appliances,Patients received clear aligner ((Invisalign, Align Technology Inc., Santa Clara, CA, USA).
Basic Science,Basic Science
Fixed orthodontic appliance,Invisalign
Sponsors
International College of Dentistry, Walailak University,
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1 clinically healthy status 2 moderate or severe crowding 3 no anti-inflammatory or antibiotics drugs use within one month prior to the study part 4 non-smokers 5 healthy periodontal tissues
Exclusion criteria
Exclusion criteria: 1 history of systemic diseases 2 taken any medication 3 presence of salivary glands disorder.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Salivary proteins Prior the treatments (T0), 3-month follow up (T1) and 6-month follow up (T2) Liquid chromatography-tandem mass spectrometry | — |
Secondary
| Measure | Time frame |
|---|---|
| Tooth alignment Prior the treatments (T0), 3-month follow up (T1) and 6-month follow up (T2) Clinical observation and radiography | — |
Countries
Thailand
Contacts
Public ContactSittichai Koontongkaew
International College of Dentistry, Walailak University
Outcome results
None listed