Psoriasis group, the study aimed to enroll 26 psoriasis patients, age between 18 to 60 years, who visited the Mae Fah Luang University hospital, Bangkok, Thailand Psoriasis, arterial stiffness, cardiovascular risk, Cardio-ankle vascular index
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: For psoriasis group, the study aimed to enroll 26 psoriasis patients, age between 18 to 60 years, who visited the Mae Fah Luang University hospital, Bangkok, Thailand, who visit the clinic for regular annual check-up visit. Exclusion criteria included personal history of psoriatic arthritis, known case of malignancy, uncontrolled severe medical conditions such as end-stage renal or liver failure and cerebrovascular disease, chronic infection such as human immunodeficiency virus (HIV) and mycobacterium tuberculosis and those subjects who currently taken some medications that directly affect arterial measurement. For the control group, this study utilized secondary data from a study entitled 'Association of Age with Carotid Intima-Media Thickness, Arterial Stiffness, and Brachial Artery Systolic Time Intervals in Thai People Undergoing a Routine Annual Physical Exam' published by V. Jularattanaporn et al. (16) with formal permission. There were 104 healthy volunteers without a personal history of psoriasis, aged between 18-60 years,
Exclusion criteria
Exclusion criteria: Exclusion criteria for psoriasis group included personal history of psoriatic arthritis, known case of malignancy, uncontrolled severe medical conditions such as end-stage renal or liver failure and cerebrovascular disease, chronic infection such as human immunodeficiency virus (HIV) and mycobacterium tuberculosis and those subjects who currently taken some medications that directly affect arterial measurement. Exclusion criteria in control group were to known cases of malignancy, uncontrolled severe medical conditions such as end-stage renal or liver failure and cerebrovascular disease, chronic infection such as HIV and tuberculosis and those subjects who are currently taken some medications that directly affect arterial measurement.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardio-ankle vascular index (CAVI) measurement were used as clinical screening tools to detect arterial stiffness. CAVI, assessed by VaSera VS-1500 device (Fukuda Denshi, Tokyo, Japan). At the enrollment visit, First visit Unit of CAVI score | — |
Secondary
| Measure | Time frame |
|---|---|
| fasting blood glucose, total cholesterol, triglyceride, high density lipoprotein-cholesterol (HDL-Chol), low density lipoprotein- cholesterol (LDL-Chol) and serum creatinine for kidney function. At the enrollment visit, First visit ml | — |
Countries
Thailand
Contacts
school of Anti-Aging and Regenerative Medicine, Mae Fah Luang University,