Diabetic kidney disease DM, DKD, Albuminuria, zinc, ESRD, CKD,Chronic kidney disease
Conditions
Interventions
Sponsors
Department of Medicine Faculty of Medicine Vajira Hospital Navamindradhiraj University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Patients with chronic kidney disease (CKD) due to type 2 diabetes in a nephrology clinic who have been diagnosed with diabetic kidney disease by a nephrologist 2. have a UACR at least 30 mg/g, confirmed by at least two separate tests conducted at least three months apart, with the most recent UACR test within the past three months 3. Patients with CKD stages 1-5 according to the KDIGO guidelines, with stage 5 patients not receiving renal replacement therapy 4. If patients are receiving Angiotensin-Converting Enzyme Inhibitors (ACEIs), Angiotensin Receptor Blockers (ARBs), Mineralocorticoid Receptor Antagonists (MRAs), or SGLT2 inhibitors, their medication doses must have remained unchanged for the past three months 5. Diabetic patients with an HbA1c level of 6.5-8.0
Exclusion criteria
Exclusion criteria: 1. Pregnant or planning to become pregnant, screened using a urine pregnancy test 2. Patients undergoing renal replacement therapy or kidney transplantation 3. Presence of heart failure based on physical examination 4. Urinary tract infection 5. Abnormal AST or ALT levels 6. History of taking any supplements or vitamins within the past three months before enrolling in the study 7. History of non-adherence to treatment or irregular follow-up visits 8. History of adverse reactions to zinc supplementation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Albuminuria 6 months Urine albumin creatinine ratio | — |
Secondary
| Measure | Time frame |
|---|---|
| Kidney function 6 months eGFR | — |
Countries
Thailand
Contacts
Public ContactNapassorn Lekwichittada
Department of Medicine Faculty of Medicine Vajira Hospital Navamindradhiraj University
Outcome results
None listed