The development of aloe vera mouthwash to decrease plaque and gingivitis.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20250311007

Enrollment

Registered

2025-03-11

Start date

2022-09-12

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health or gingivitis aloe vera mouthwash gingivitis

Interventions

Volunteers used mouthwash 2 times daily, 15 ml each time, morning and before bedtime for 1 month. There was a washing period of 2 weeks. ,Volunteers used mouthwash 2 times daily, 15 ml each time, morn

Experimental Drug,Active Comparator Drug,Placebo Comparator Drug

aloe vera ,chlorhexidine ,placebo

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1 Having 20 teeth or more 2 Having less than 4 mm probing depth 3 No fixed orthodontic appliance or removable denture

Exclusion criteria

Exclusion criteria: 1 Systemic disease that affects periodontium ex diabetes mellitus 2 Allergic to chlorhexidine aloe vera garlic onion and tulip 3 Antibiotic treatment for the last 3 months 4 Smoker 5 pregnant or lactation 6 Alcoholism

Design outcomes

Primary

Measure	Time frame
Plaque index 1 month after using mouthwash (Plaque index (Silness and Loe)	—

Secondary

Measure	Time frame
Bleeding on probing 1 month after using mouthwash Bleeding on probing at 6 teeth,Gingival index (Sillness and Loe) 1 month after using mouthwash Gingival index of 6 teeth	—

Countries

Thailand

Contacts

Public ContactAurasri Komchornrit

Srinakharinwirot university

ornsri@g.swu.ac.th660814314512

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026