15 years old and over Pregnant women with Iron deficiency anemia Pregnant women Iron deficiency anemia Oral iron supplementation
Conditions
Interventions
Ferrous fumarate (200mg) 1 tab po pc morning + Triferdine 1 tab po pc morning for 1 month
,Ferrous fumarate (200mg) 1 tab po pc morning + Triferdine 1 tab po pc hs for 1 month
Experimental Drug,Active Comparator Drug
Once-daily iron supplementation ,Twice-daily iron supplementation
Sponsors
None listed
Eligibility
Sex/Gender
Female
Age
15 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Pregnant women aged 15 years or older with singleton between 15 to 32 weeks gestation attending antenatal care at Hat Yai Hospital 2.Serum ferritin lower 50 ng/mL 3.Hemoglobin levels lower 11 g/dL (second trimester) or lower 10.5 g/dL (third trimester) 4.Mean corpuscular volume (MCV) lower 80 fL
Exclusion criteria
Exclusion criteria: 1.Hyperemesis gravidarum 2.Thalassemia disease 3.Chronic kidney disease (stage 3 or higher) 4.Gastrointestinal diseases affecting absorption such as chronic peptic ulcers/ Crohn s disease/ or ulcerative colitis 5.Cancer 6.History of intolerance to iron supplementation (Grade 2 or higher side effects) 7.Blood transfusion or IV iron supplementation within the past 3 months 8.Visual/ speech/ or hearing impairments
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare serum ferritin level after one month of once-daily vs. twice-daily iron supplementation 1 month ferritin | — |
Secondary
| Measure | Time frame |
|---|---|
| serum Hemoglobin level change after one month 1 month serum Hemoglobin level,Neonatal outcomes: preterm birth rates and low birth weight 1 month preterm birth rates ,low birth weight,Side effects of iron supplementation 1 month Nausea vomiting score | — |
Countries
Thailand
Contacts
Public ContactChanamonwan Sukkerd
Hatyai hospital
Outcome results
None listed