Outcomes of Repeated versus Non-Repeated Blood Cultures in Gram-Negative Bacilli Bacteremia Among Immunocompetent Patients: A Multicenter Randomized Controlled Trial (REACT 1)

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20250302006

Enrollment

180

Registered

2025-03-02

Start date

2025-07-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with gram-negative rod bacteremia immunocompetent, bacteremia, Gram-negative rod

Interventions

repeat hemoculture within 96 hours,no repeat hemoculture

Experimental Other,No Intervention Other

repeated hemoculture,control

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Age 18 years and older 2. Immunocompetent patients 3. Have gram-negative rod grew in hemoculture

Exclusion criteria

Exclusion criteria: decide not to involve vital signs not stable

Design outcomes

Primary

Measure	Time frame
recurrent bacteremia 30 days hemoculture	—

Secondary

Measure	Time frame
mortality 30 days death at end of study	—

Countries

Thailand

Contacts

Public ContactJackrapong Bruminhent

Faculty of Medicine Ramathibodi Hospital

jbruminhent@gmail.com022011581

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026