Outcomes of Repeated versus Non-Repeated Blood Cultures in Gram-Negative Bacilli Bacteremia Among Immunocompromised Patients: A Multicenter Randomized Controlled Pilot Trial

Outcomes of Repeated versus Non-Repeated Blood Cultures in Gram-Negative Bacilli Bacteremia Among Immunocompromised Patients: A Multicenter Randomized Controlled Pilot Trial (REACT 2)

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20250220005

Enrollment

100

Registered

2025-02-20

Start date

2025-07-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Immunocompromised conditions Immunocompromised, bacteremia, gram-negative rod, transplant

Interventions

repeated hemoculture within 96 hours

Experimental Other

Repeated hemoculture arm

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adult age 18 years and older Have immunocompromised conditions

Exclusion criteria

Exclusion criteria: not stable in vital signs Decide not to participate

Design outcomes

Primary

Measure	Time frame
Recurrent bacteremia 30 days hemoculture	—

Secondary

Measure	Time frame
mortality 30 days alive at the end of study	—

Countries

Thailand

Contacts

Public ContactJackrapong Bruminhent

Faculty of Medicine Ramathibodi Hospital

jackrapong.brm@mahidol.ac.th022011581

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026