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Evaluation of Efficacy and Safety of the 675-nm Red Laser for Treatment of Atrophic Acne Scars in Asians.

Evaluation of Efficacy and Safety of the 675-nm Red Laser for Treatment of Atrophic Acne Scars in Asians

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250218009
Enrollment
16
Registered
2025-02-18
Start date
2024-03-04
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrophic acne scar acne scar, 675 nm laser

Interventions

Patients were treated with 675-nm red laser 3 sessions every 4 weeks. Then they were instructed to follow up at 1, 3, and 6 months after last treatment.
Experimental Device

Sponsors

Faculty of Medicine Siriraj hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Thai Male or Female, age 20-50 years old 2. Diagnosed with moderate acne scar by Qualitative global scarring grading system

Exclusion criteria

Exclusion criteria: 1. Patients who are pregnant, lactating, and postpartum within 1 year 2. Patients with history of Cushing syndrome or Ehlers-Danlos syndrome 3. Patients with other skin diseases, or having infection at the area of face 4. Immunocompromised patients 5. Patients with hypertrophic scar or keloid 6. Patients with photosensitivity disorder 7. Patients with cancers or skin cancers 8. Patients with mental disorders 9. Received Botulinum toxin injection, collagen biostimulators, platelet-rich plasma, laser, threads or energy-based devices within the last 6 months before participating in the research project 10. Patients who taking oral isotretinoin within 6 months and/or using topical retinoids within 3 months

Design outcomes

Primary

MeasureTime frame
volume depression baseline, 1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment, 3 months after 3rd treatment, 6 months after 3rd treatment Antera 3D ,texture baseline, 1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment, 3 months after 3rd treatment, 6 months after 3rd treatment Antera 3D

Secondary

MeasureTime frame
Erythema index baseline, 1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment, 3 months after 3rd treatment, 6 months after 3rd treatment Mexameter,Melanin index baseline, 1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment, 3 months after 3rd treatment, 6 months after 3rd treatment Mexameter,Goodman and Baron's Quantitative Global Acne Scarring Grading System baseline, 1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment, 3 months after 3rd treatment, 6 months after 3rd treatment by two dermatologists,Safety baseline, 1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment, 3 months after 3rd treatment, 6 months after 3rd treatment Adverse event

Countries

Thailand

Contacts

Public ContactWoraphong Manuskiatti

Department of Dermatology, Faculty of medicine Siriraj hospital, Mahidol university

woraphong.man@mahidol.ac.th024197000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026