Atrophic acne scar acne scar, 675 nm laser
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Thai Male or Female, age 20-50 years old 2. Diagnosed with moderate acne scar by Qualitative global scarring grading system
Exclusion criteria
Exclusion criteria: 1. Patients who are pregnant, lactating, and postpartum within 1 year 2. Patients with history of Cushing syndrome or Ehlers-Danlos syndrome 3. Patients with other skin diseases, or having infection at the area of face 4. Immunocompromised patients 5. Patients with hypertrophic scar or keloid 6. Patients with photosensitivity disorder 7. Patients with cancers or skin cancers 8. Patients with mental disorders 9. Received Botulinum toxin injection, collagen biostimulators, platelet-rich plasma, laser, threads or energy-based devices within the last 6 months before participating in the research project 10. Patients who taking oral isotretinoin within 6 months and/or using topical retinoids within 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| volume depression baseline, 1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment, 3 months after 3rd treatment, 6 months after 3rd treatment Antera 3D ,texture baseline, 1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment, 3 months after 3rd treatment, 6 months after 3rd treatment Antera 3D | — |
Secondary
| Measure | Time frame |
|---|---|
| Erythema index baseline, 1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment, 3 months after 3rd treatment, 6 months after 3rd treatment Mexameter,Melanin index baseline, 1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment, 3 months after 3rd treatment, 6 months after 3rd treatment Mexameter,Goodman and Baron's Quantitative Global Acne Scarring Grading System baseline, 1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment, 3 months after 3rd treatment, 6 months after 3rd treatment by two dermatologists,Safety baseline, 1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment, 3 months after 3rd treatment, 6 months after 3rd treatment Adverse event | — |
Countries
Thailand
Contacts
Department of Dermatology, Faculty of medicine Siriraj hospital, Mahidol university