Community acquired sepsis Community acquired septic shock Procalcitonin Community-Acquired Infections Sepsis Duration of Therapy Anti-Bacterial Agents
Conditions
Interventions
Procalcitonin levels were monitored on days 0, 2, and 5 of therapy. The treatment plan and duration of antibiotic were determined by the primary physician.,No procalcitonin monitoring. The treatment p
Experimental Procedure/Surgery,No Intervention Procedure/Surgery
Procalcitonin monitor arm,Usual care arm
Sponsors
Bhumibol Adulyadej Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age over 18 years old 2. Community-acquired sepsis according to SIRS criteria presenting at ED 3. Enrolled within 24 hours after initial diagnosis
Exclusion criteria
Exclusion criteria: 1. Suspected sepsis not resulting from a bacterial infection 2. Aim as palliative treatment 3. Expected treatment duration of less than 5 days or plan more then 21 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of antibiotic treatment after enrollment until stop antibiotic date count | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospitalization days after hospitalization until discharge date count,Mortality within 28 days after enrolled count,Proportion of procalcitonin levels lower than 0.5 on day 5. day 5 Procalitonin level on day 5 ,Factor associated with duration of antibiotic After enrollment until stop antibiotic Compare the baseline characteristics such as age, sex, incidence of septic shock, laboratory results, source of infection, and identified pathogens between the groups. | — |
Countries
Thailand
Contacts
Public ContactNatthakit Chavapradit
Bhumibol Adulyadej Hospital
Outcome results
None listed