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The Role of the Pulpal Microbiome in the Success of Primary Tooth Pulpotomy

The Effect of the Pulpal Microbiome in the Success of Primary Tooth Pulpotomy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250214003
Enrollment
72
Registered
2025-02-14
Start date
2025-04-13
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental caries, periapical pathology Pulpal microbiome, Primary tooth pulpotomy

Interventions

Dental caries that has reached 2/3 of the dentin,Dental caries that has reached the pulp
Active Comparator Drug,Experimental Drug
Group 1,Group 2

Sponsors

Ataturk University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 10 Years

Inclusion criteria

Inclusion criteria: 1.Patients included in the study must be between the ages of 6 and 10 and must not have any disabilities. 2.There should be no signs of periapical pathology in the affected primary tooth. 3.The affected primary tooth should be asymptomatic (no spontaneous pain). 4.Radiographically, the caries should have reached or extended beyond 2/3 of the dentin.

Exclusion criteria

Exclusion criteria: 1.They are younger than 6 years old or older than 10 years old. 2.They have any disability. 3.Any periapical pathology is detected in the affected tooth. 4.There is spontaneous pain in the affected primary tooth. 5.Radiographically, the caries has not reached 2/3 of the dentin.

Design outcomes

Primary

MeasureTime frame
Microbial Analysis 12 Months Polymerase Chain Reaction

Secondary

MeasureTime frame
Clinical and Radiographic Success 12 months Periapical radiography

Countries

Turkey

Contacts

Public ContactSera Simsek Derelioglu

Ataturk University

simseksera@gmail.com539 363 3388

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026