Study on prevalence and clinical characteristics of non-gonococcal gram-negative septic arthritis Gram negative septic arthritis
Conditions
Interventions
Patients with culture-confirmed gram-positive septic arthritis ,Patients with culture-confirmed non-gonococcal gram-negative septic arthritis
Other,Other
Gram positive septic arthritis,Gram negative septic arthritis
Sponsors
Srinagarind Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 years old or older 2. Admitted in Srinagarind Hospital during 1 January 2015 to 24 October 2024 3. Diagnosed by primary doctor of septic arthritis and recored ICD-10 code with M00 (pyogenic arthritis), M01 (direct infections of joints in infectious and parasitic diseases classified elsewhere), or T84.5 (infection and inflammatory reaction due to internal joint prosthesis) in principle diagnosis, co-morbidity or complications 4. Positive bacterial culture from synovial fluid or blood (collected within a timeframe close to arthrocentesis)
Exclusion criteria
Exclusion criteria: 1. Cannot access data from medical records or insufficient data 2. Not meet the definition* of septic arthritis after reviewing medical records * Definition For naive joints ICD-10 codes M00 (Pyogenic arthritis), M01 (Direct infections of joints in infectious and parasitic diseases classified elsewhere), and T84.5 (Infection and inflammatory reaction due to internal joint prosthesis) from the inpatient medical records of Srinagarind Hospital between January 1, 2015, and October 24, 2024. Patients must be diagnosed with septic arthritis by a primary physician, with documentation indicating joint pain, swelling, redness, or warmth. Joint aspiration must have been performed, and bacterial growth must be confirmed through culture of synovial fluid or blood (collected within a timeframe close to joint aspiration). For prosthetic joints Patients must meet at least one of the following diagnostic criteria: 1. Presence of a sinus tract connecting the prosthetic joint to the skin. 2. Evidence of inflammation from histopathological examination of periprosthetic tissue obtained during surgery. 3. Presence of pus around the prosthetic joint observed during surgical exposure. 4. Positive bacterial culture from synovial fluid or periprosthetic tissue obtained during surgery, indicating a high-virulence pathogen (e.g., Staphylococcus aureus). In cases where common floras, such as coagulase-negative staphylococci or Cutibacterium acnes, are cultured (which may represent true infection or contamination), positive results must be confirmed from at least two separate specimens.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of non gonococcal gram-negative septic arthritis 1 January 2015 to 24 October 2024 Data collected from electronic medical record | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical characteristics of non gonococcal gram-negative septic arthritis 1 January 2015 to 24 October 2024 Data collected from electronic medical records | — |
Countries
Thailand
Contacts
Public ContactAthit Niramaitaworn
Faculty of medicine, Khon Kaen University
Outcome results
None listed