Evaluation of subfoveal choroidal thickness and retinal microvasculature using enhanced depth imaging-optical coherence tomography (EDI-OCT) and OCT angiography (OCTA) in paediatric and adolescent diabetes mellitus enhanced depth imaging-optical coherence tomography (EDI-OCT),OCT angiography OCTA),
Conditions
Interventions
The patient will visit the ophthalmology clinic for an eye assessment, which includes visual acuity testing, auto refraction, non contact tonometry, fundus photography using the Optos machine, EDI OCT
s cooperation. All the mentioned tests are non invasive and do not involve any radiation. There have been no reports of long term side effects associated with these tests.
Patients will be provided w
s cooperation. All the mentioned tests are non invasive and do not involve any radiation. There have been no reports of long term side effects associated with these tests.
Healthy volunteers will be
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
diabetes mellitus group,Control group
Sponsors
Faculty of Medicine Siriraj Hospital, Mahidol University
Eligibility
Sex/Gender
All
Age
8 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 8 to 18 years with a diagnosis of diabetes mellitus (type 1 or type 2) for more than 1 year. 2. Healthy age-matched controls will be included.
Exclusion criteria
Exclusion criteria: 1. History of prematurity 2. Poor fundus view due to any ocular disease such as ocular inflammatory disease, corneal opacities, cataract and vitreous haze 3. Pre-existing retinal pathologies such as chorioretinal scar, myelinated nerve fibers, and retinal drusen that may change the retinal thickness 4. Refractive error with spherical equivalence of more than -6D 5. History of ocular injury such as penetrating injury, traumatic optic neuropathy and ocular uveitis 6. History of any ocular surgeries 7. Systemic diseases other than diabetes 8. Patient with intraocular pressure more than 21mmHg or diagnosed glaucoma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vision assessment - visual acuity measurement, autorefraction, non-contact intraocular pressure test, Optos retinal imaging, EDI-OCT, and OCTA. | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Public ContactProfessor Laongsri Atchaneeyasakul
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed