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Impact of implementing rapid diagnostic testing (multiplex PCR-based blood culture identification) among hospitalized pediatric patients

Impact of implementing rapid diagnostic testing (multiplex PCR-based blood culture identification) among hospitalized pediatric patients at King Chulalongkorn Memorial Hospital

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20250205003
Enrollment
300
Registered
2025-02-05
Start date
2024-10-06
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diagnostic tool for bacteremia in hospitalized children bacteremia, pediatric, rapid diagnostic test

Interventions

Retrospectively review 150 cases of hospitalized children with positive blood culture and identified pathogen using conventional blood culture,Prospectively recruit 150 cases of hospitalized children
Diagnostic,Diagnostic
Standard conventional blood culture, Rapid diagnostic test for identification pathogen in blood culture

Sponsors

BioFire Diagnostics, LLC
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 15 Years

Inclusion criteria

Inclusion criteria: Patients aged less than 15 years who are hospitalized in a general pediatric ward or pediatric intensive care unit (PICU) at King Chulalongkorn Memorial Hospital and have been identified positive blood culture.

Exclusion criteria

Exclusion criteria: 1. Patients who are hospitalized in a nursery / special care unit (SCN) / neonatal intensive care unit (NICU) ward 2. Incomplete medical records of the primary outcomes e.g. data on antibiotic use

Design outcomes

Primary

MeasureTime frame
Timing to antibiotic targeted therapy Time starts from the time from the first dose of antibiotic to the first dose of targeted antibiotic therapy or antimicrobial discontinuation for contaminants. Timing to antibiotic targeted therapy

Secondary

MeasureTime frame
Percentage of changing antibiotic according to the result 24 hours after receiving RDT result Percentage of changing antibiotic according to the result

Countries

Thailand

Contacts

Public ContactSuvaporn Anugulruengkitt

Faculty of Medicine, Chulalongkorn University

suvaporn.a@chula.ac.th022564930

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026