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Reliability of Preoperative Assessment of Meningioma Stiffness by Magnetic Resonance Elastography

Reliability of Preoperative Assessment of Meningioma Stiffness and Meningioma-brain adhesion by MR Elastography

Status
Unknown
Phases
Early Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250203008
Enrollment
50
Registered
2025-02-03
Start date
2024-03-13
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Meningioma Meningioma, Magnetic Resonance Elastroagraphy, stiffness , adhesion

Interventions

MR Elastrography
Experimental Other

Sponsors

Faculty of Medicine, Khon Kaen University, Thailand
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1 Patients over 18 years of age, previously diagnosed meningioma based on MRI imaging. 2 Patients scheduled for surgery at Srinagarind Hospital, Khon Kaen University.

Exclusion criteria

Exclusion criteria: 1 Patients with tumor size less than 2.5 cm. As the previous study (Yu et al. (2022)) shows that MRE tends to underestimate shear stiffness in smaller tumors, especially those less than 2 cm. in size. 2 Patients undergoing needle biopsy only. 3 Patients with recurrent or residual tumors at the same site after prior surgery. However, if these patients scheduled for surgery of a new tumor in the other location will not be excluded.

Design outcomes

Primary

MeasureTime frame
Tumor Stiffness After the study measurement on MRI station by drawing region of interest (ROI ) at different areas in the tumor mass and measure the stiffness in Kilo Pascal (kPa)

Secondary

MeasureTime frame
Tumor -brain adhesion after the study Grading degree of interface between tumor and surrounding brain by using eyeball technique from slip interface images as number 1,2,3 (1.complete 2.partial 3.no interface)

Countries

Thailand

Contacts

Public ContactWarinthorn Phuttharak

Khon Kaen University

pwarin@kku.ac.th6643348389

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026