chronic rhinusinusitis with or without nasal polyp allergic rhinitis non allergic rhinitis Nasal irrigation adverse effects, Oxymetazoline, Chronic rhinosinusitis without nasal polyp, Chronic rhinosinusitis with nasal polyp, Allergic rhinitis, Non allergic rhinitis
Conditions
Interventions
patient in this arm uses oxymetazoline nasal spray before irrigation with nasal saline twice daily ,patient in this arm uses placebo (NSS) nasal spray in the same packaging as oxymetazoline before irr
Experimental Drug,Placebo Comparator Drug
oxymetazoline nasal spray before nasal irrigation,placebo before nasal irrigation
Sponsors
-
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.patients with chronic rhinosinusitis without nasal polyp, chronic rhinosinusitis with nasal polyp, allergic rhinitis, non-allergic rhinitis with intranasal corticosteroids treatment 2.age 18-70 years
Exclusion criteria
Exclusion criteria: 1.patients who previously had sinus surgery 2.nasal blockage from tumors 3.pregnant and breastfeeding patients 4.allergies to oxymetazoline 5.patients with hypertension, diabetes, prostatic hypertrophy, glaucoma and history of cardiac ischemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| side effects from nasal irrigation: nasal burning, nasal blockage, nasal dripping, nose bleed, headaches, otalgia, aural fullness 2 weeks questionnaire | — |
Secondary
| Measure | Time frame |
|---|---|
| rebound congestion 2 weeks questionnaire | — |
Countries
Thailand
Contacts
Public ContactAlexandra Cadet
Rajavithi Hospital
Outcome results
None listed