Healthy untrained male ecdysteroid, muscle strength, resistance training, detraining, insulin-like growth factor-1, fatty acid oxidation, insulin resistance
Conditions
Interventions
The 20E group consumed approximately 30 mg of 20-hydroxyecdysone derived from asparagus by-product extract per day,The PLA group consumed 2 capsules of maltodextrin per day.
Experimental Dietary Supplement,Placebo Comparator No treatment
20 hydroxyecdysone supplementation group (20E group),PLA group
Sponsors
The Graduate Program Scholarship from the Graduate School, Kasetsart University and the Thailand Toray Science Foundation (TTSF)
Eligibility
Sex/Gender
Male
Age
18 Years to 25 Years
Inclusion criteria
Inclusion criteria: 1. Healthy males with less than one year of resistance training experience. 2. Participants who had not engaged in resistance training within the past six months.
Exclusion criteria
Exclusion criteria: 1. Participants with any major metabolic disorders, such as heart disease, diabetes, or thyroid disease. 2. Participants with musculoskeletal conditions that could impair their ability to exercise or complete the required tests. 3. Participants taking medications, nutritional supplements, or ergogenic aids (e.g., creatine, androstenedione, myostatin inhibitors, or prohormones) that could influence the study outcomes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body composition prior to training, after 12 weeks of training, and after 6 and 12 weeks of detraining dual-energy X-ray absorptiometry,Body circumferences prior to training, after 12 weeks of training, and after 6 and 12 weeks of detraining a flexible inelastic tape,Blood samples and snalysis included IGF-1, free testosterone, cortisol, aspartate transaminase, alanine transaminase, alkaline phosphatase, blood urea nitrogen, and creatinine prior to training, after 12 weeks of training, and after 6 and 12 weeks of detraining commercial assay kits and a clinical chemistry analyzer,Blood samples and analysis included FBG, insulin, free fatty acids prior to training and after 12 weeks of training commercial assay kits and a clinical chemistry analyzer,Muscular strength prior to training, after 12 weeks of training, and after 6 and 12 weeks of detraining The one-repetition maximum (1RM) was determined using an indirect method on the leg press, followed by bench presses,Resting energy expenditure and substrate utilization prior to training and after 12 weeks of training gas analyzer,Substrate utilization during exercise prior to training and after 12 weeks of training gas analyzer | — |
Secondary
| Measure | Time frame |
|---|---|
| dietary intake prior to training, after 12 weeks of training, and after 6 and 12 weeks of detraining 24-dietary record | — |
Countries
Thailand
Contacts
Public ContactJatuporn Phoemsapthawee
Faculty of Sports and Health Science, Kasetsart University
Outcome results
None listed