Patients with sign of photo damaged skin facial rejuvenation, 675 nm laser
Conditions
Interventions
patient were treated with 675 nm laser 3 session every 4 weeks then they were instruct to follow up at 1 month 3 month and 6 months post treatment
Experimental Device
675 nm laser
Sponsors
Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 20-60 years, both males and females. 2. Individuals with early-stage sun-damaged skin, assessed by at least one of the following criteria: 2.1. Uneven skin tone. 2.2. Fine lines. 2.3. Dry skin. 2.4. Skin sagging. 3.Thai individuals of Asian descent. 4. Volunteers who willingly agree to participate in the project and consent to receiving laser treatment according to the research protocol.
Exclusion criteria
Exclusion criteria: 1. Pregnant or breastfeeding women. 2. Volunteers with a history of platelet disorders, blood clotting disorders, anemia, liver disease, cancer, or autoimmune diseases. 3. Volunteers who smoke or have a history of excessive alcohol consumption. 4. Volunteers with dermatitis, wounds, or facial skin infections. 5. Volunteers with a history of allergy to anesthetics. 6. Volunteers with a history of regular use of hormones, contraceptive injections, or oral contraceptives, as well as regular use of NSAIDs. 7. Volunteers with a history of taking medications affecting blood clotting, such as aspirin or anticoagulants. 8. Volunteers with a history of facial tightening treatments, such as lifting devices or thread lifting, within 6 months prior to participating in the study. 9. Volunteers with a history of receiving facial filler injections within 6 months prior to participating in the study. 10. Volunteers with a history of platelet-rich plasma (PRP) injections to the face within 6 months prior to participating in the study. 11. Volunteers with a history of botulinum toxin injections to the face within 6 months prior to participating in the study. 12. Volunteers with a history of collagen-stimulating laser treatments on the face, such as picosecond laser, erbium: YAG laser, Fractora, or E-matrix laser, within 6 months prior to participating in the study. 13. Volunteers with a history of keloid scars. 14. Volunteers with psychiatric disorders diagnosed by a psychiatrist. 15. Volunteers who do not permit photography for treatment evaluation purposes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average Wrinkle and Texture baseline, treatment2, treatment3, 1 month, 3 months and 6 months Antera,hydration baseline, treatment2, treatment3, 1 month, 3 months and 6 months Corneometer,skin firmness baseline, treatment2, treatment3, 1 month, 3 months and 6 months Cutometer,melanin, erythema baseline, treatment2, treatment3, 1 month, 3 months and 6 months Mexameter,Modified Fitzpatrick Wrinkles Scale baseline, treatment2, treatment3, 1 month, 3 months and 6 months score | — |
Secondary
| Measure | Time frame |
|---|---|
| physician assessment baseline, treatment2, treatment3, 1 month, 3 months and 6 months score,patient assessment score baseline, treatment2, treatment3, 1 month, 3 months and 6 months score,pain score baseline, treatment 2, treatment3 score | — |
Countries
Thailand
Contacts
Public ContactWoraphong Manuskiatti
Faculty of Medicine Siriraj Hospital, Mahidol University
Outcome results
None listed