Outpatients aged 50-85 years scheduled for elective colonoscopy Prucalopride, colonoscopy, Polyethylene glycol, bowel preparation, colon cancer, Boston bowel preparation scale, Ottawa scale
Conditions
Interventions
Prucalopride 2 mg plus 2 liters of polyethylene glycol,Placebo plus 2 liters of polyethylene glycol
Experimental Drug,Placebo Comparator Drug
Prucalopride plus 2 liters polyethylene glycol,Placebo plus 2 liters polyethylene glycol
Sponsors
Department of Medicine, Phramongkutklao Hospital and College of Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Eligible participants were outpatients aged 50-85 years scheduled for elective colonoscopy.
Exclusion criteria
Exclusion criteria: Exclusion criteria included 1. American Society of Anesthesiologists (ASA) Physical Status Class 3 or 4 2. History of inflammatory bowel disease 3. History of Colonic diverticulosis 4. Allergies to polyethylene glycol (PEG) or prucalopride 5. Congestive heart failure 6. Chronic kidney disease with volume overload 7. Morbid obesity 8. Current use of laxatives within 2 weeks prior to colonoscopy 9. Current use of opioids within 2 weeks prior to colonoscopy 10. Previous inadequate bowel preparation 11. History of bowel resection 12. History of bariatric surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy of bowel preparation at the day of colonoscopy Boston bowel preparation scale and Ottawa bowel preparation scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events at the day of colonoscopy Symptom severity was rated on a five-point scale,Adenoma detection rate 4 weeks after full report of pathology Adenoma detection rate | — |
Countries
Thailand
Contacts
Public ContactAnuchit Suksamai
Phramongkutklao Hospital and College of Medicine
Outcome results
None listed