Intrathecal nalbuphine can reduce side effects of morphine (eg.postoperative nausea vomiting, itching) Intrathecal nalbuphine, intrathecal morphine, postoperative analgesia
Conditions
Interventions
Intrathecal morphine dose 0.2 mg,Intrathecal nalbuphine dose 0.4 mg,Intrathecal nalbuphine dose 0.8 mg
Morphine 0.2 mg,Nalbuphine 0.4 mg,Nalbuphine 0.8 mg
Sponsors
Nakhonpathom Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: Pregnancy was indicated cesarean section ASA classification II or III Choice of anesthesia is spinal block well communicate to identified pain score and side effects
Exclusion criteria
Exclusion criteria: Patient denied spinal block technique Bupivacaine, morphine or nalbuphine allergy Contraindication for spinal block e.g. infection on skin injection, hypotension, thrombocytopenia, coagulopathy, increase ICP Drug abuse, alcoholism, Anti psychiatric drugs use BMI > 40 kg/m2 fetal distress, abruptio placenta, rupture uterine, placenta previa
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete analgesia after intrathecal injection to VAS more than 0 Pain score | — |
Secondary
| Measure | Time frame |
|---|---|
| Effective analgesia after intrathecal injection to VAS more than 3 or patient request rescue IV fentanyl Pain score | — |
Countries
Thailand
Contacts
Public ContactDudsadee Chatpoom
Nakhonpathom Hospital
Outcome results
None listed