Scheduling follow-up appointments and treatment for patients can be challenging
Conditions
Interventions
i. Radiofrequency Ablation (RFA) via Endoscopic Ultrasound:
1. The equipment used includes an ultrasound endoscope (EG-3870K: Pentax Corporation and Ultrasound Scanner NOBLUS: Hitachi), a Monopolar RF
Experimental Procedure/Surgery,Active Comparator Procedure/Surgery
Radiofrequency Ablation (RFA) group,Chemotherapy group
Sponsors
Ratchadapisek Somphote Endowment Fund Chulalongkorn University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with advanced pancreatic adenocarcinoma confirmed by pathology, 2. Inoperable as determined by radiologic findings or expert surgeon opinion (AJCC 8th stage III, TNM stage T1-3 or N2, T4 any N, M0). 3. ECOG performance status 2.
Exclusion criteria
Exclusion criteria: 1. Patients for whom RFA cannot be performed due to technical issues. 2. Pregnant patients. 3. Patients previously treated for pancreatic cancer with standard therapies. 4. Patients with uncorrectable coagulopathy. 5. Patients who do not consent to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| survival rate 6-month lab results (Liver Function Tests), side effects (Nausea and Vomiting), pain medication dosage, and quality of life | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse effects (Hematologic, Gastrointestinal) 6 months European Organisation For Research And Treatment Of Cancer-Quality Of Life (Functioning Scales, Symptom Scales) | — |
Countries
Thailand
Contacts
Public ContactPradermchai Kongkam
chulalongkorn university
Outcome results
None listed