Enlarged facial pores botulinum toxin dermal filler injectables neuromodulators pore size skin quality
Conditions
Interventions
Combination of BoNT-A and Hyaluronic acid filler injection,Botulinum toxin A injection
Experimental Procedure/Surgery,Experimental Procedure/Surgery
Combined BoNT-A + HA filler,BoNT-A
Sponsors
Faculty of Medicine Ramathibodi Hospital Mahidol University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 65 years old 2. Healthy with no serious underlying diseases 3. Has enlarged pores on both sides of the face equally 4. Able to attend medical appointments and comply with the research protocol 5. Willing to participate in the research by providing signed consent
Exclusion criteria
Exclusion criteria: 1. Having an infection or inflammation of the skin in the area to be treated. 2. Having wounds or open sores in the area to be treated. 3. Having an immunodeficiency or any type of neuromuscular disease. 4. Having a history of skin cancer. 5. Having active acne vulgaris that is not under control. 6. Having a history of keloid scarring. 7. Having a history of allergy to anesthetics, fillers, or botulinum toxin. 8. Having a history of purchasing botulinum toxin. (This might relate to concerns about counterfeit or improperly handled products.) 9. Having undergone surgery in the treatment area within 6 months prior to the study. 10. Having received facial treatments with laser, dermabrasion, peeling, or radiofrequency in the cheek area within 3 months prior to the study. 11. Having received filler injections in the cheek area within 1 year. 12. Having a history of accidents and having metal implants in the area to be treated. 13. Having a history of recurrent herpes infection. 14. Having a history of taking vitamin A derivatives in the past 3 months. 15. Having a history of COVID-19 infection within 14 days prior to the start of the study. 16. Having dental root disease or having undergone dental root procedures. 17. Being pregnant or breastfeeding. 18. Refusing or withdrawing from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pore volume 0,4,8,12,16,24 weeks Antera 3D,Skin roughness 0,4,8,12,16,24 weeks Antera 3D,Pore evaluation 0,4,8,12,16,24 weeks Visual assessment score | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects 4,8,12,16,24 weeks Patient record | — |
Countries
Thailand
Contacts
Public ContactVasanop Vachiramon
Division of Dermatology, Department of Medicine, Faculty of Medicine Ramathibodi hospital, Mahidol University
Outcome results
None listed