1. Clinically diagnosed with Parkinson disease stages 2 and 3 as assessed by the modified Hoehn and Yahr scale 2. Healthy adults for comparative with individuals with Parkinson Parkinson disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.1 Inclusion criteria for Parkinson disease or PD group 1) Clinically diagnosed with PD stages 2 (bilateral disease, without impairment of balance) to 3 (mild to moderate bilateral disease; some postural instability; physically independent) as assessed by the modified Hoehn and Yahr scale 2) The age groups between 45 and 75 years 3) Taking PD medication regularly for at least a month or to have maintained stable anti-PD medication without any changes for at least one month prior to the study. This criterion aimed to minimize potential confounding effects on movement performance, particularly those related to variations in antiparkinsonian drug dosage during testing. 4) Able to use smart phone for download metronome application, either by the participant or their caregiver 5) Able to walk independently without any assistive device 6) Able to follow commands and instructions. 1.2 Inclusion criteria 1) The age and sex of the matched groups with PD ranged between 45 and 75 years. 2) Able to understand and follow commands and instructions 3) Able to walk independently without any assistive devices 4) Able to use smart phone for download metronome application, either by the participant or their caregiver 5) Score about 24 or more for TMSE and score of 25 or more for the MoCA
Exclusion criteria
Exclusion criteria: 1) Have a verified clinical diagnosis of a condition that could influence test and STS movement, for example severe vestibular dysfunction 2) Have a comorbidity with severe systemic illness, severe signs and symptoms of musculoskeletal issues, such as having a knee/hip prosthesis that may influenced STS performance 3) Visual and hearing problems that cannot be corrected with the use of aids.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Movement time of sit to stand task from markerless motion capture 1 week second,2.Angular velocity curves of the trunk, ankle, knee, and hip joints in the sagittal plane of sit to stand task from markerless motion capture 1 week deegree per sec,3.Reaction time of sit to stand task from markerless motion capture 1 week seconds,4.Time to complete of Five time sit to stand task 1 week sencond,5.Time to complete Timed Up and Go test 1 week second | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. The total score from the Mini BESTest 1 week score,2. The total score of the Parkinson Disease Questionnaire 8 1 week score,3. The total score of the Fall Efficacy Scale International 1 week score | — |
Countries
Thailand
Contacts
Mahidol University