Effect of isometric handgrip exercise on cognitive function and biomarkers in patients with mild cognitive impairment

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20250111003

Enrollment

Registered

2025-01-11

Start date

2025-10-22

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mild cognitive impairment mild cognitive impairment biomarker isometric handgrip exercise

Interventions

Isometric handgrip exercise,Standard care

Experimental Behavioral,No Intervention No treatment

Isometric handgrip exercise,Control

Eligibility

Sex/Gender

All

Age

55 Years to 75 Years

Inclusion criteria

Inclusion criteria: patients with mild cognitive impairment

Exclusion criteria

Exclusion criteria: patients with contraindication to resistant exercise or hand deformity patients with cognitive intervention or other neurological disease

Design outcomes

Primary

Measure	Time frame
cognitive function 12 weeks cognitive test	—

Secondary

Measure	Time frame
Biomarkers 12 weeks Cytokine panel	—

Countries

Thailand

Contacts

Public ContactSathinee Supphapitiphon

King Chulalongkorn Memorial hospital

sppsathinee@gmail.com0816236351

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026