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Endoscopic mucosal resection versus SpeedboatTM submucosal dissection in 20-30mm non-pedunculated left-sided colon polyps: a multicentre randomized control trial

Endoscopic mucosal resection versus SpeedboatTM submucosal dissection in 20-30mm non-pedunculated left-sided colon polyps: a multicentre randomized control trial

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20250110001
Enrollment
40
Registered
2025-01-10
Start date
2025-02-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The underlying concern is the potential for these larger adenomatous polyps to progress to colorectal cancer Speedboat, Endoscopic mucosal resection, colon polyps

Interventions

1. Submucosal injection using normal saline and methylene blue. 2. Removal of polyp by hot snare EMR 3. Clipping of post-polypectomy defect will be at the discretion of the endoscopist.,1. Submucosal
Active Comparator Procedure/Surgery,Experimental Procedure/Surgery
Endoscopic mucosal resection group,Speedboat group

Sponsors

excellence center for gastrointestinal endoscopy, King Chulalongkorn Memorial Hospital, Bangkok
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patient who are aged 18 or older. 2. Patient with non-pedunculated polyp size 20-30 mm in the left side of colon

Exclusion criteria

Exclusion criteria: 1. Patient who has underlying familial adenomatous polyposis syndrome 2. Patient who has underlying inflammatory bowel disease 3. Patient with previous attempts at resection of the lesion 4. Lesion has signs of submucosal involvement on endoscopy. 5. Lesion involving the dentate line. 6. Patient who is pregnant 7. Patient with a bleeding tendency 8. Patient who is unwilling to provide written informed consent.

Design outcomes

Primary

MeasureTime frame
Resection rates 6 months surveillance colonoscopy and biopsies of the resection scar will be obtained to confirm the absence of recurrence on histology

Secondary

MeasureTime frame
Rates of bleeding 14 days post-procedure complications

Countries

Thailand

Contacts

Public ContactPradermchai Kongkam

chulalongkorn university

kongkam@hotmail.com022564356

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026