The efficacy of coblation vs. bipolar radiofrequency inferior turbinate reduction in the management of nasal obstruction in OSA patients: A double-blinded randomized controlled trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

TCTR

Registry ID

TCTR20250107005

Enrollment

Registered

2025-01-07

Start date

2024-12-09

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nasal obstruction in patients with obstructive sleep apnea (OSA) requiring continuous positive airway pressure (CPAP) ventilation. inferior turbinate reduction, radiofrequency abrasion, coblation, nasal obstruction, obstructive sleep apnea, continuous positive airway pressure ventilation

Interventions

Radio-frequency Inferior Turbinate Reduction with Bipolar RaVoRTM Needle Electrode with the CURIS 4 MHz radio-frequency generator, Sutter Medizintechnik GMBH, Freiburg, Germany,Radio-frequency Inferio

Active Comparator Device,Active Comparator Device

Bipolar Radio-frequency Inferior Turbinate Reduction,Coblation Inferior Turbinate Reduction

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Adult (Age 20-65 years) OSA patients 2. Using CPAP for at least 3 months 3. Had symptoms of nasal obstruction via Visual Analogue Scale Evaluation (VAS) of more than 5 4. Bilateral inferior turbinate hypertrophy of grades II to III via the Friedman grading system

Exclusion criteria

Exclusion criteria: 1. Patients with previous nasal or sinus surgery, septal deformity, nasal polyposis, sinusitis, and nasal cavity tumor 2. Patient with coagulopathy, cardiac pacemaker or other implanted electronic devices 3. Patient denial

Design outcomes

Primary

Measure	Time frame
Nasal obstruction symptom at 3 and 6 months after end of intervention Visual Analogue Scale Evaluation (VAS),Nasal cavity air flow at 3 and 6 months after end of intervention Peak Nasal Inspiratory Flow (PNIF)	—

Secondary

Measure	Time frame
Reduction of the Apnea-Hypopnea Index (AHI) and CPAP Pressure at 6 months after end of intervention Polysomnogram,CPAP compliance at 6 months after end of intervention CPAP report,Operation time Intrapoerative Operation Record,Complication at intraoperative, 2 weeks, 3 and 6 months after end of intervention Medical Record	—

Countries

Thailand

Contacts

Public ContactNawat Ungkhara

Faculty of Medicine Ramathibodi Hospital, Mahidol University

count-junior@hotmail.com0917746174

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 10, 2026