Femoral neck fracture Hip fracture in elderly Femoral neck fracture Hip fracture in elderly Partial hip replacement Periarticular injection Magnesium sulfate
Conditions
Interventions
50% MgSO4, 2 mL (Atlantic Laboratory Corporation Ltd., Thailand)
0.5% Bupivacaine, 40 mL (Aspen, Australia)
Ketorolac, 30 mg (Siu Guan Chemical Industrial, Chai Yi, Taiwan) (1 mL)
Epinephrine, 1 mg (T
Experimental Drug,No Intervention Drug
M-PAI,C-PAI
Sponsors
Navamindradhiraj University Research Fund
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged between 60 and 90 years., 2. Diagnosed with intracapsular neck of femur fracture and underwent bipolar partial hip replacement surgery., 3. Classified as ASA physical status class I-III in terms of physical risk assessment.
Exclusion criteria
Exclusion criteria: 1. Patients who are bedridden or unable to walk before surgery., 2. Patients with morbid obesity, defined as a BMI greater than 40 kg/m2., 3. Patients with a history of allergy to any ingredients in the periarticular injection solution, including Ketorolac, Bupivacaine, and Epinephrine., 4. Patients with a history of using analgesic drugs specified in the study., 5. Patients with a history of opioid use or chronic pain within 3 months before surgery., 6. Patients with neurological diseases affecting walking, such as hemiplegia, paralysis, or muscle weakness., 7. Patients with renal failure or impaired kidney function, defined as a glomerular filtration rate (GFR) less than 30 mL/min/1.73m2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Numeric Pain Scale q4h until 48 hours, 72 h Postoperative pain score | — |
Secondary
| Measure | Time frame |
|---|---|
| Opioid use 24, 48 and 72 hours Postoperative Morphine use,Side effect from opioid 24, 48 and 72 hours Incidence of side effect from opioid,Functional Hip Score 2, 6, 12 weeks Harris Hip Score,Complications IPD, 2, 6, 12 weeks Complication from surgery | — |
Countries
Thailand
Contacts
Public ContactIttiwat Onklin
Faculty of Medicine, Vajira Hospital, Navamindradhiraj University
Outcome results
None listed