To study accuracy (sensitivity, specificity, PPV, NPV, LR+, LR-) of the ROX-HR index, compare to the ROX index at 0, 2, 6, 12, 24 hours after HFNC initiation to predict HFNC failure in patient with pneumonia and non-pneumonia sepsis. The patients who is suspected sepsis with acute respiratory failure and required HFNC as oxygen supplement will be included, defined by the all following criteria: aged greater than 18 years, patients suspected sepsis, the HFNC will be applied when patients have sig
Conditions
Interventions
Patients with suspected sepsis and ARF received HFNC and continued more than 48 hours without escalate to intubation or NIV,Patients with suspected sepsis and ARF received HFNC and within 48 hours aft
Treatment,Treatment
HFNC success group,HFNC failure group
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patient age greater than 18 years who present to emergency department with pneumonia sepsis and non-pneumonia sepsis 2. Need for high-flow nasal cannula oxygen supplement.
Exclusion criteria
Exclusion criteria: 1. Immediate intubation 2. Cardiac arrest 3. Referred from/refer to other hospital 4. Were initiated with NIV or cycled between NIV-HFNC or multiple HFNC initiated time-points during staying in EDs 5. DNR or DNI order 6. Too short duration on HFNC (< 1 hours)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| study accuracy of ROX index at 0, 2, 6, 12, 24 hours after HFNC initiation sensitivity, specificity, PPV, NPV, LR+, LR- | — |
Secondary
| Measure | Time frame |
|---|---|
| study accuracy of ROX-HR index at 0, 2, 6, 12, 24 hours after HFNC initiation sensitivity, specificity, PPV, NPV, LR+, LR- | — |
Countries
Thailand
Contacts
Public ContactChuenruthai Angkoontassaneeyarat
Mahidol University
Outcome results
None listed