Kokumi Effects in Enhancing Taste Perception in Head and Neck Cancer Survivors after Radiotherapy and Chemotherapy

Kokumi Effects in Enhancing Taste Perception in Head and Neck Cancer Survivors after Radiotherapy and Chemotherapy: An Experimental Study

Status

Unknown

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20241221002

Enrollment

Registered

2024-12-21

Start date

2024-10-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dysgeusia (abnormal taste sensation) in head and neck cancer patients Dysgeusia, abnormal taste sensation, head and neck cancer, radiotherapy, chemotherapy

Interventions

Food sample is mixed with Glutathione aiming to enhance the taste characteristics and taste threshold of patient with dysgeusia. After that, the subjects will taste food sample without Glutathione add

Experimental Drug,Experimental Drug

Glutathione,Control

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Head and neck cancer patients 2. Age over 18-70 year old 3. Radiotherapy and/or chemotherapy 4. Having symptoms of dysgeusia (defined by patient complainant of symptoms)

Exclusion criteria

Exclusion criteria: 1. Previous hemi to total glossectomy 2. Other feeding routes apart from oral feeding including nasogastric tube or gastrostomy tube

Design outcomes

Primary

Measure	Time frame
Taste sensory characteristic At the time of intervention Visual analog scale	—

Secondary

Measure	Time frame
Taste sensory threshold At the time of intervention Threshold	—

Countries

Thailand

Contacts

Public ContactPraeploy Tungyingyong

Faculty of Medicine, Chulalongkorn university

entmdcu@gmail.com022564000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026