Contact lens wearer contact lens corneal epithelial thickness
Conditions
Interventions
Individuals with history of at least one year of regular use of contact lens wear
Regular use of contact lens wear is defined as an average continuous contact lens wear for at least 1 day per week and
Basic Science,Basic Science
Contact lens wearers,Control
Sponsors
Ratchadapisek Research Funds Type I
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. History of at least one year of regular use of contact lens wear, 2. Individual without history of regular contact lens wear (control)
Exclusion criteria
Exclusion criteria: 1. Diagnosed with corneal ectasia or ocular surface disease (other than dry eye, meibomian gland dysfunction and allergic conjunctivitis) such as thermal or chemical burn, bullous keratopathy, corneal dystrophy, corneal edema, infectious keratitis, pterygium, history of Stevens-Johnson syndrome (SJS), toxic epidermal necrosis (TEN), ocular cicatricial pemphigoid (OCP), or vernal keratoconjunctivitis, 2. History of ocular surface surgery involving limbus or using intraoperative chemotherapy (eg. mitomycin-C and 5-fluorouracil) such as pterygium surgery, trabeculectomy, limbal stem cell transplant, or ocular surface neoplasia excision with cryotherapy, 3. History of head and neck radiotherapy, 4. Current use of topical antiglaucoma for more than 1 year, 5. Unable to obtain anterior segment optical coherence tomography (AS-OCT), 6. Discontinued contact lenses for more than 1 month before recruitment, 7. Unable to recall a detailed history of contact lens wear
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Corneal epithelial thickness at the time of recruitment anterior segment optical coherence tomography | — |
Secondary
| Measure | Time frame |
|---|---|
| Dry Eyes at the time of recruitment Thai Ocular surface disease index (T-OSDI) score and Dry Eye Workshop (DEWS) staging,Limbal stem cell deficiency (LSCD) clinical score at the time of recruitment Limbal stem cell deficiency (LSCD) clinical score | — |
Countries
Thailand
Contacts
Public ContactPhattharaphong Tantichariyangkul
Faculty of Medicine, Chulalongkorn University
Outcome results
None listed