desaturation during induction of general anesthesia in obese children apneic oxygenation low-flow nasal cannula induction of general anesthesia obese children
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. patients with overweight or obesity 2. scheduled to undergo elective surgery under general anesthesia with endotracheal tube or laryngeal mask airway 3. ASA physical status I-II 4. admitted at least 1 day before surgery
Exclusion criteria
Exclusion criteria: 1. morbid obesity 2. severe cardiopulmonary disease with baseline SpO2 less than 95% at room-air 3. severe OSA with AHI score more than 10 4. history of asthmatic attack in the past 1 month 5. severe respiratory tract infection 6. fever with body temperature more than 38 degrees Celsius 7. expected difficult ventilation 8. aspiration risk requiring rapid sequence induction 9. history of allergy to anesthetic drugs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| safe apnea time SpO2 equals to 95% time spent from ending of mask ventilation until Spo2 equals to 95% (seconds) or reaching the limit of 5 minutes, whichever occured first | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of desaturation SpO2 less than 95% number of cases that SpO2 less than 95% occurred,lowest SpO2 lowest SpO2 percent of SpO2,CO2 retention in the first 10 breath after resuming mask ventilation highest end-tidal CO2 in the first 10 breath after resuming mask ventilation | — |
Countries
Thailand
Contacts
Queen Sirikit National Institute of Child Health