patient undergoing lumbar spine surgery lumbar spine surgery
Conditions
Interventions
no intrathecal injection,intrathecal nalbuphine 1 mg before wound closure
no intervention,intrathecal nalbuphine
Sponsors
Navamindradhiraj university
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. patients undergoing lumbar spine surgery from the L2 level to the sacrum 2. Patients aged between 18-70 years 3. Patients with an American Society of Anesthesiologists (ASA) physical status of I-III
Exclusion criteria
Exclusion criteria: 1.Patients allergic to the study drug or its components 2.Patients with uncontrolled asthma 3.Patients with ischemic heart disease 4.Patients with elevated intracranial pressure 5.Patients with impaired liver or kidney function (glomerular filtration rate <30 ml/min) 6.Patients with abnormal blood coagulation 7.Patients with a history of gastrointestinal ulcers or bleeding 8.Patients with a history of continuous opioid use for 3 months or more, except in cases where opioids have been discontinued and are not for chronic pain conditions 9.Patients unable to assess pain levels 10.Pregnant or breastfeeding patients 11.Patients undergoing minimally invasive surgery 12.Patients who refuse to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pain 48 hours after operation Numerical rating scale | — |
Secondary
| Measure | Time frame |
|---|---|
| morphine consumption 48 hours after operation patient-controlled analgesia (PCA) ,nausea vomiting 48 hours after operation Nausea and vomiting score ,sedation 48 hours after operation sedation score,respiratory depression 48 hours after operation respiratory rate | — |
Countries
Thailand
Contacts
Public Contactwanutchaporn sujarittham
Faculty of medicine Vajira hospital, Navamindradhiraj university
Outcome results
None listed