Changes in anthropometric parameters, blood pressure, blood glucose levels, lipid profiles, liver and kidney function, and inflammatory markers among adults at risk of metabolic syndrome. herbal extract, supplement, metabolic syndrome
Conditions
Interventions
The control group will be asked to consume a placebo made from corn starch, consisting of 2 capsules per day (1,000 mg/capsule) continuously for 84 days.,The experimental group will be asked to consum
Control,Herbal extract
Sponsors
Hopeful Co., Ltd.
Eligibility
Sex/Gender
All
Age
30 Years to 59 Years
Inclusion criteria
Inclusion criteria: 1. Males and females aged 30-59 years. 2. Individuals at risk of metabolic syndrome who meet at least one of the following criteria: 2.1) Waist circumference over 80 cm (female) or over 90 cm (male) 2.2) Blood pressure over 130/85 mmHg 2.3) Fasting blood glucose level over 100 mg/dL 2.4) Triglyceride level over 150 mg/dL 2.5) HDL cholesterol level < 50 mg/dL (female) or < 40 mg/dL (male) 3. Able to consume experimental food throughout the study. 4. Able to read, write, and communicate Thai. 5. Willing volunteers to participate in the research project with full awareness.
Exclusion criteria
Exclusion criteria: 1. Individuals who are undergoing treatment or taking medication for chronic non-communicable diseases such as coronary artery disease, stroke, diabetes, liver disease, chronic kidney disease, cancer, thyroid issues, etc. 2. Individuals who have abnormalities in the digestion and absorption of nutrients or experience chronic fatigue. 3. Individuals who have consumed dietary supplements or herbs more than 2 times per week in the 4 weeks before participating in the study or during the research. 4. Individuals with dietary patterns differing from a regular diet or those who have altered their physical activity patterns within 6 months before participating in the research. 5. Smoking more than 5 cigarettes per day. 6. Drinking alcoholic beverages more than 14 drinks per week. 7. Pregnant or planning to become pregnant within 6 months or currently breastfeeding. 8. Individuals allergic to the food ingredients used in the tested meal replacement products. 9. Unable to cooperate in recording food consumption. 10. Being a participant in any other study during the study period. 11. Those who are unable to follow all study procedures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in health indicators among adults at risk of metabolic syndrome before and after consuming a dietary supplement made from herbal extracts for 84 days. at 12-week of the intervention Anthropometric assessment and biochemical assessment | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in health indicators between the control group and the experimental group consuming herbal extracts dietary supplement over 84 days at 12-week of the intervention Anthropometric assessment and biochemical assessment | — |
Countries
Thailand
Contacts
Public ContactChanchira Phosat
Faculty of Public Health, Mahidol University
Outcome results
None listed