Healthy volunteer, Healthy volunteer Microbiome Metabolite Transcriptome
Conditions
Interventions
All volunteers must consume Hang rice-germ powder as dietary supplement 30 mg/kg of body by dissolving in hot water 2 times/day, a total of 2 weeks. The blood, urine and feces sample will be collected
the first time is the day before consumption, the second time is 2 weeks after consumption and the third time is 3 weeks after back to a usual diet. The researcher team will provide the powder in a pl
Experimental Dietary Supplement
Sponsors
Khon Kaen University
Thailand Science Research and Innovation
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-40 years old 2. BMI less than 25 kg/m2 3. No pregnant 4. No treatment with any medication during the project including prebiotics, probiotics, or other supplements that modify the composition of gut microbiota 5. No smoking 6. Healthy and no underlying disease by the health screening check up such as blood pressure, pulse, heart/lung screening by doctor, fasting blood sugar, and lipid levels are within normal range.
Exclusion criteria
Exclusion criteria: 1. Have underlying disease 2. Have treatment with medication 3. Using prebiotics, probiotics, or other supplements that modify the composition of gut microbiota 4. Smoking 5. Pregnant 6. Blood pressure, pulse, heart/lung screening by doctor, fasting blood sugar, and lipid levels are not in normal range
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiome The first time is the day before consumption, the second time is 2 weeks after consumption and the third time is 3 weeks after back to a usual diet Genomics, 16S rRNA gene sequencing | — |
Secondary
| Measure | Time frame |
|---|---|
| Metabolite the first time is the day before consumption, the second time is 2 weeks after consumption and the third time is 3 weeks after back to a usual diet Metabolimics, LC-MS/MS | — |
Countries
Thailand
Contacts
Public ContactWatcharin Loilome
: Faculty of Medicine, Khon Kaen University
Outcome results
None listed