patients aged 18 to 65 years were diagnosed with acute otitis externa by an otorhinolaryngologist within 3 weeks acute otitis externa, Neomycin sulphate, Polymyxin B sulphate, Gramicidin, Ofloxacin
Conditions
Interventions
combined ototopical drug (polymyxin B 5,000 iu, neomycin 2 mg and gramicidin 0.025 mg)
1. lying down and the ear positioned upward
2. two drops can then be placed along the side of the ear canal
3. l
Active Comparator Drug,Active Comparator Drug
Neomycin sulphate, Polymyxin B sulphate, Gramicidin combined ear drop ,Ofloxacin ear drop
Sponsors
KHON KAEN UNIVERSITY
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. patients aged 18 to 65 years 2. diagnosed with acute otitis externa by an otorhinolaryngologist within 3 weeks
Exclusion criteria
Exclusion criteria: 1. contraindications for use of Neomycin sulphate, Polymyxin B sulphate, Gramicidin, Ofloxacin 2. patients who have taken ototopical ear drop in the last 3 weeks 3. patients who have other ears' problem e.g. tympanic membrane perforation, infection 4. during treat otitis externa with other medications 5. patients who can not communicate e.g. multiple handicaps 6. patients who can not come to follow-up 7. severe ear canal swelling, can not evaluate ear drum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| improvement of acute otitis externa at 1 and 2 weeks after treated with ear drops clinical symptoms score | — |
Secondary
| Measure | Time frame |
|---|---|
| Pathogen of otitis externa 1 and 2 weeks after start ototopical drug Ear tissue culture | — |
Countries
Thailand
Contacts
Public ContactPaunchanit Warathisapong
Khonkaen university
Outcome results
None listed