Proximal humerus fracture with patients who undergoing ORIF proximal humerus fracture tranexamic acid blood loss
Conditions
Interventions
tranexamic acid 15 mg/kg dilute with NSS 100 ml IV drip in 30 min before surgery 15 min,not receive tranexamic acid
Experimental Drug,No Intervention No treatment
Sponsors
khonkaen hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: patients with proximal humerus fracture 1. Displaced two part surgical neck fracture 2. Displaced three part fracture 3. Displaced four part fracture
Exclusion criteria
Exclusion criteria: 1. Displaced greater tuberosity fracture 2. Anemia 3. Coagulopathy 4. thrombocytopenia 5. Chronic kidney disease 6. history of thromboembolism 7. Receive anticoagulant 8. allergy tranexamic acid 9. history of seizure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| total blood loss at the end of surgery and 2 hour post operation Estimate blood volume and hematocrit pre and post operative 2 hour | — |
Secondary
| Measure | Time frame |
|---|---|
| rate of blood transfusion day 3 post operation number of transfusion,percentage hemoglobin change 2 hour post operation CBC post operative 2 hour,complication 3 day post operation rate of event,intraoperative blood loss at the end of surgery volume of blood during surgery,volume of drain output 3 day post operation volume of drain,length of stay patient discharge number of day until patient discharge,Post operative hemoglobin post operative 2 hour CBC post operative 2 hour,change in hemoglobin 2 hour post operation difference pre and 2 hour post dose | — |
Countries
Thailand
Contacts
Public Contactwedchasak bunnak
khonkaen hospital
Outcome results
None listed