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An effectiveness of 4%Lidocaine spray on post-operative cough in Microlaryngeal surgery

An effectiveness of 4%Lidocaine spray on post-operative cough in Microlaryngeal surgery

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20241116003
Enrollment
64
Registered
2024-11-16
Start date
2024-10-21
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-operative cough in Microlaryngeal surgery Laser, microscopy

Interventions

Apply Intraoperative topical laryngotracheal anesthesia using 4% Lidocaine spray under direct instillation,Not apply Intraoperative topical laryngotracheal anesthesia
Experimental Drug,No Intervention No treatment
Intraoperative topical laryngotracheal anesthesia used,Controlled

Sponsors

Faculty of Medicine Research Grant Khon Kaen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. age 18-65 years old 2. Patients with laryngeal disorder scheduled for Microlarygeal surgery under general anesthesia. 3. Patient scheduled for Microlaryngeal surgery under Jet Ventillation. 4. Patient informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patient with neurological pathology that affected general sensation. 2. Patient who has allergic reaction to Lidocaine. 3. Pregnancy woman 4. Patient with hemodynamic instability 5. Patient who suffer from chronic pain or needed analgesic drug. 6. Patient with chronic cough 7. Attention to tracheostomy 8. Patient who has risk for aspiration 9. Heavy smoking 10. History of respiratory tract infection for 1 month prior surgery 11. Obesity 12. Risk of difficult intubation

Design outcomes

Primary

MeasureTime frame
Primary outcome At 30 minutes (T1), 1 hour (T2) after remove direct laryngoscope Effective to prevent postoperative cough grading by cough scale

Secondary

MeasureTime frame
Secondary outcome At 1 hour(T2), 24 hours(T3) after remove direct laryngoscope Effective to reduce postoperative sore throat by Visual Analogue Scale (VAS)

Countries

Thailand

Contacts

Public ContactPunnika Damrongwiriyakul

Faculty of Medicine, Khon Kaen University

Punnda@kku.ac.th0818427397

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026