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Inferior Vena cava Collapsibility index (IVC-CI) guided preloading to reduce hypotension following spinal block in lower limb surgery: a comparative study

Inferior Vena cava Collapsibility index (IVC-CI) guided preloading to reduce hypotension following spinal block in lower limb surgery: a comparative study

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20241116002
Enrollment
86
Registered
2024-11-16
Start date
2023-08-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The patient is undergoing lower limb surgery with spinal anesthesia. Spinal block, Hypotension, Inferior venacava collapsibility index ( IVC-CI )

Interventions

If the IVC CI (Inferior Vena Cava Collapsibility Index) measurement is greater than 36%, it indicates a high degree of collapsibility of the major veins, which may suggest a deficiency in blood or flu
ultrasound inferior vena cava collapsibility index (IVC-CI) ,standard care

Sponsors

Faculty of Medicine, Srinakharinwirot University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing non-urgent lower limb surgery 2. Patients aged 18-75 years 3. ASA classification I-III

Exclusion criteria

Exclusion criteria: 1. patients who did not consent to participate 2. contraindications to spinal anesthesia 3. underlying hypertension. 4. moderate to severe cardiac conditions such as coronary artery disease or valvular heart disease 5. pregnancy 6. body mass index (BMI) of 40 or greater 7. poor visualization of major veins via ultrasound 8. anesthetic allergies 9. stage 4 or higher chronic kidney disease 10. chronic lung disease limiting fluid administration 11. liver failure 12. anemia, defined as a hemoglobin level of 7 mg/dL or less.

Design outcomes

Primary

MeasureTime frame
incidence of hypotension after end anesthesia 24 hour inferior vena cava collapsibility index (IVC-CI) by ultrasound

Secondary

MeasureTime frame
Compare the amount of vasopressor, volume of fluids, intraoperative and postoperative complications. after end anesthesia 24 hour amount of vasopressor drug, fluid volume and complications

Countries

Thailand

Contacts

Public ContactWanida Chongarunngamsang

Faculty of Medicine, Srinakharinwirot University

waple0508@gmail.com66892756345

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026