Chronic obstructive pulmonary disease(COPD) patients with moderate to severe following GOLD guideline COPD
Conditions
Interventions
The tDCS device will use to deliver anodal-tDCS to the scalp. The electrode consists of 2 electrodes which scale 3.5x6.5 centimeters. Anodal-tDCS electrode will be placed on M1 region on scalp followi
Sham-tDCS,tDCS
Sponsors
Research Fund for Supporting Lecturer to Admit High Potential Student to Study and Research on His Expert Program Year 2021 (641JH214)
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Post-bronchodilator of FEV1/FVC < 70% 2. Post-bronchodilator of FEV1 30-80% of predicted value 3. Age 40-85 years 4. Non-regular exercise (<3times/week and <30 min/day)
Exclusion criteria
Exclusion criteria: 1. Other respiratory diseases such as asthma, bronchiectasis, pulmonary hypertension 2. Acute exacerbation within a month before starting these studies 3. Congestive heart failure, angina pectoris, and third-degree A-V block 4. The presence of orthopedic or neuromuscular conditions interfering with the ability to perform resistance exercises such as herniated disc, lumbar stenosis, and muscle weakness 5. No metallic implants near electrodes and no use of pacemaker 6. No history of neurological disorders such as stroke
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Exercise capacity at 1st days after stimulatin 1 days (Immediately test) at Day 6th (Post-test after stimulation for 5 days), and 7th day after the last stimulation(Follow-up test) Six-minutes walk test | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory muscle strength at 1st days after stimulatin 1 days (Immediately test) at Day 6th (Post-test after stimulation for 5 days), and 7th day after the last stimulation(Follow-up test) Maximum inspiratory pressure,Respiratory muscle strength at 1st days after stimulatin 1 days (Immediately test) at Day 6th (Post-test after stimulation for 5 days), and 7th day after the last stimulation(Follow-up test) Maximum exspiratory pressure,Lung function at 1st days after stimulatin 1 days (Immediately test) at Day 6th (Post-test after stimulation for 5 days), and 7th day after the last stimulation(Follow-up test) Spirometry test,Physical performance at 1st days after stimulatin 1 days (Immediately test) at Day 6th (Post-test after stimulation for 5 days), and 7th day after the last stimulation(Follow-up test) Time up and Go test,Physical performance at 1st days after stimulatin 1 days (Immediately test) at Day 6th (Post-test after stimulation for 5 days), and 7th day after the last stimulation(Follow-up test) One leg stance test,Physical performance at 1st days after stimulatin 1 days (Immediately test) at Day 6th (Post-test after stimulation for 5 days), and 7th day after the last stimulation(Follow-up test) Five time sit-to-stand test,Physical performance at 1st days after stimulatin 1 days (Immediately test) at Day 6th (Post-test after stimulation for 5 days), and 7th day after the last stimulation(Follow-up test) 4-meters gait speed test,Physical performance at 1st days after stimulatin 1 days (Immediately test) at Day 6th (Post-test after stimulation for 5 days), and 7th day after the last stimulation(Follow-up test) Hand grip strength | — |
Countries
Thailand
Contacts
Public ContactChalermkiat sawasdee
Faculty of Medicine, Khon Kaen University
Outcome results
None listed