Prolong latency period of pregnancy maternal adverse outcomes neonatal adverse outcomes azithromycin, erythromycin, prolong latency period, neonatal adverse outcomes, maternal adverse outcomes
Conditions
Interventions
Pregnant women with rupture of membranes between 24-34 weeks of gestation who received ampicillin 2 g IV every 6 hours and azithromycin 1 g for the first 48 hours followed by amoxycillin 500 mg 3 time
Health Services Research,Health Services Research
azithromycin,erythromycin
Sponsors
Faculty of Medicine, Siriraj Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Azithromycin group 1. Pregnant women with rupture of membranes between 24-<34 weeks of gestation 2. Pregnant women who received ampicillin 2 g IV every 6 hours and azithromycin 1 g for the first 48 hours followed by amoxycillin 500 mg 3 times daily for 5 days until 7 days to prolong the latency period Erythromycin group 1. Pregnant women with rupture of membranes between 24-<34 weeks of gestation 2. Pregnant women who received ampicillin 2 g IV every 6 hours and erythromycin 250 mg orally every 6 hours for the first 48 hours followed by amoxycillin 250 mg 3 times daily and erythromycin 250 mg 4 times daily for 5 days until 7 days to prolong the latency period
Exclusion criteria
Exclusion criteria: 1. Pregnant women who are not taking drugs to prolong the latency period 2. Pregnant women who are contraindicated to take drugs to prolong the latency period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| prolong latency period 7 days days | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse maternal outcomes 7 days intensive care unit admission,adverse neonatal outcomes 7 days neonatal intensive care unit admission | — |
Countries
Thailand
Contacts
Public ContactSaifon Chawanpaiboon
Siriraj Hospital, Mahidol University
Outcome results
None listed