Reducing in hemoglobin or hematocrit in the patient who diagnosed with spondylosis with radiculopathy and underwent conventional open laminectomy with posterior instrumented fusion with using bone wax before insertion of pedicular screw Lumbar spondylosis, Conventional open surgery, poster instrumented fusion, bone wax
Conditions
Interventions
- Bone wax is in the shape of a rectangular prism, measuring 20 millimeters in width, 50 millimeters in length, and 2 millimeters in thickness. The weight of each piece of bone wax in a package is 2.5
Experimental Drug,No Intervention No treatment
bone wax group (Intervention group),conventional group (control group)
Sponsors
Department of Orthopedic, Faculty of medicine, Chiang Mai University
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Patients in the group with degenerative bone and joint diseases who have been diagnosed with degenerative disc disease at the lumbar level, lumbar spinal stenosis, and spondylolisthesis, along with symptoms caused by nerve compression. 2. Patients in category 1 are planned for surgery with conventional open laminectomy and posterior instrument fusion. 3. Age 20 years and older who can provide informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of allergy to bone wax or allergic to materials/substances containing wax. 2. Patients with bleeding disorders (coagulopathy) or those who have difficulty with bleeding control. 3. Patients currently using medications that affect blood coagulation, which may lead to prolonged bleeding, including antiplatelet or anticoagulant medications. 4. Patients with a history of coagulation issues in various systems of the body (venous thromboembolic events). 5. Low hemoglobin levels before surgery (Hb < 8 g/dL). 6. Patients who are currently pregnant or breastfeeding. 7. Female patients currently using estrogen hormone therapy. 8. Patients with impaired kidney function, with creatinine clearance < 30 ml/min. 9. Patients at high risk for spinal surgery (American Society of Anesthesiologists) class 4 and above.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemoglobin and hematocrit at postoperative since skin incision to 72 hours postoperation Laboratory investigations: esp. serial complete blood count and intraoperative blood loss by Weighing of the gauze | — |
Secondary
| Measure | Time frame |
|---|---|
| blood transfusion since skin incision to 72 hours postoperation unit in PRC, FFP and SDP or Platelet conc.,Intraoperative time since skin incision to skin closure minutes,Acute complications Since skin incision to discharge from hospital Medical records | — |
Countries
Thailand
Contacts
Public ContactRATTHAKORN KHAMSRI
Faculty of Medicine, Chiang Mai University
Outcome results
None listed